TABSECTIONITEM

• Alphabetical
  

  Maricedes Acosta-Martinez

  Neuroendocrinology, Neuroinflammation, and Placenta Physiology

  Maricedes.Acosta@stonybrook.edu

  

  Michael Airola

  The Airola lab studies the molecular details of lipid metabolism and transport and seeks to develop new pharmacological tools that inhibit lipid-modifying enzymes for the treatment of cancer and fungal disease

  Michael.airola@stonybrook.edu

  

  Ivet Bahar

  Our lab is interested in computer-aided design and development of small molecule modulators of protein function including orthosteric and allosteric drugs, and in modeling biomolecular interactions and their systemic effects at multiple scales.

  ivet.bahar@stonybrook.edu

  

  Elizabeth Boon

  Chemical Biology, Enzymology, Bioinorganic Chemistry, and Spectroscopy

  elizabeth.boon@stonybrook.edu

  

  Mark Bowen

  Neurobiology. Protein supertertiary structure. Fluorescence microscopy.

  Mark.Bowen@StonyBrook.edu

  

  Eric Brouzes

  Analyzing heterogeneity of cancer tissues

  eric.brouzes@stonybrook.edu

  

  Christopher Brownlee

  Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

  christopher.brownlee@stonybrook.edu

  

  Nicholas Carpino

  Positive and Negative Regulation of T cell Receptor Signaling

  nicholas.carpino@stonybrook.edu

  

  Isaac Carrico

  Chemical Biology, Bioorganic Chemistry and Protein Engineering

  isaac.carrico@stonybrook.edu

  

  Fei Chen

  Environmental risk factors in carcinogenesis with emphasis on metabolic and epigenetic reprograms during malignant transformation of the cells.

  Fei.Chen.1@stonybrook.edu

  

  Leonard Cheung

  Pituitary function in physiology, aging, and disease

  Leonard.Cheung@stonybrook.edu

  

  Jun Chung

  Mechanism of cancer invasion and metastasis

  Jun.Chung@stonybrookmedicine.edu

  

  Chris Clarke

  Sphingolipid metabolism and signaling in tumorigenesis.

  Christopher.clarke@stonybrookmedicine.edu

  

  Holly Colognato

  Extracellular matrix in the brain: roles during development and during neurodegeneration

  holly.colognato@stonybrook.edu

  

  Mehdi Damaghi

  Tumor evolution and adaptation in their microenvironment using spatial single cell technologies

  Mehdi.Damaghi@stonybrook.edu

  

  Bruce Demple

  Cellular Systems to Counteract Oxidative Damage

  bruce.demple@stonybrook.edu

  

  Camila Dos Santos

  Epigenetic dependencies of normal and malignant breast development, with a focus on understanding paths to prevent cancer development and to attenuate the aggressiveness of already established cancer

  dossanto@cshl.edu

  

  Congwu Du

  In vivo optical imaging of neuronal-glio-vascular interactions and the effects of drug-elicited brain functional changes

  congwu.du@stonybrook.edu

  

  Joshua Dubnau

  The effects of healthy aging on brain function, and on the mechanisms of age related neurodegenerative disorders. We specialize in the impacts of retrotransposons and endogenous retroviruses as drivers of aging and neurodegeneration, with a particular emphasis on signaling between glia and neurons. Our model organism of choice is the fruit fly, Drosophila, mainly because flies rule.

  Joshua.Dubnau@stonybrook.edu

  

  Grigori Enikolopov

  Stem cells; neurogenesis; imaging; signal transduction

  Grigori.Enikolopov@StonyBrookMedicine.edu

  

  Michael Frohman

  Lipid Signaling: Roles in mitochondrial biology, spermatogenesis, diabetes, immune function, the CNS, platelet activation, and cancer; - Imaging Pancreatic β-cells using metabolomics and MRI

  michael.frohman@stonybrook.edu

  

  Miguel Garcia-Diaz

  Mechanisms of mitochondrial gene expression/Mechanisms of DNA synthesis and repair

  miguel.garcia-diaz@stonybrook.edu

  

  Shaoyu Ge

  To examine the functional integration of new neurons into brain circuits

  shaoyu.ge@stonybrook.edu

  

  Berhane Ghebrehiwet

  C1q receptor mediated cellular responses with particular emphasis on inflammation and microbial infection

  

  Steven Glynn

  X-ray crystallography, mechanistic biochemistry and protein design techniques to uncover the operating principles of energy-dependent proteolytic machines in mitochondria

  steven.glynn@stonybrook.edu

  

  Yusuf Hannun

  Lipid mediators of cancer cell signaling

  yusuf.hannun@stonybrookmedicine.edu

  

  Galadriel Hovel-Miner

  Discovery of novel genes and pathways associated with drug resistance in trypanosomatid parasites

  Galadriel.Hovel-Miner@stonybrook.edu

  

  Helen Hsieh

  Necrotizing Enterocolitis (NEC) and Neurodevelopment: the Role of Inflammation in Brain Development

  helen.hsieh@stonybrookmedicine.edu

  

  Chi-Kuo Hu

  We study the biology of dormancy and its interaction with development and aging, using an intriguing research organism of the African killifish.

  chi-kuo.hu@stonybrook.edu

  

  Leemor Joshua-Tor

  Structural Biology of gene expression, DNA replication, and small RNA biology

  leemor@cshl.edu

  

  Martin Kaczocha

  Neuroscience, acute and chronic pain, drug development, lipid signaling

  Martin.Kaczocha@StonyBrook.edu

  

  Hyungjin Kim

  DNA damage repair and cancer therapeutics; mechanisms of cancer drug actions and therapy response

  Hyungjin.kim@stonybrook.edu

  

  David Komatsu

  Biotechnology, Biology

  david.komatsu@stonybrook.edu

  

  Pawan Kumar

  IL-17 and IL-22 mediated intestinal mucosal host defense

  pawan.kumar@stonybrook.edu

  

  Scott Laughlin

  Chemical Biology & Neuroscience

  Scott.Laughlin@stonybrook.edu

  

  Feng-Qian Li

  Signaling: Cell Signaling, Cancer, Stem cells, Protein trafficking and Disease

  feng-qian.li@stonybrook.edu

  

  Ke Jian (Jim) Liu

  Molecular mechanisms of metal carcinogenesis; DNA repair and somatic mutations

  kejian.liu@stonybrookmedicine.edu

  

  Ed Luk

  How cells organize chromatin structure to accommodate and control gene expression

  ed.luk@stonybrook.edu

  

  Michael Mak

  Mechanobiology and biophysics in cancer and development; biofabrication of ultra-realistic tissues and organoids for disease modeling and regeneration; computational modeling and biophysical informatics

  michael.mak@stonybrook.edu

  

  Peng Mao

  DNA repair and cancer mutations

  Peng.Mao@stonybrookmedicine.edu

  

  Sandeep Mallipattu

  Our research program focuses on investigating the molecular mechanisms involved in the development and progression of kidney disease.

  Sandeep.Mallipattu@stonybrookmedicine.edu

  

  Benjamin Martin

  Molecular basis of stem cell development and cancer pathogenesis

  benjamin.martin@stonybrook.edu

  Luis Martinez

  p53 alterations in cancer

  luis.martinez@stonybrookmedicine.edu

  

  David McKinnon

  Molecular Physiology of Neuronal Firing Properties

  David.McKinnon@stonybrook.edu

  

  W. (Todd) Miller

  Signal transduction by tyrosine kinases

  Todd.Miller@stonybrook.edu

  

  Lisa Miller

  The chemical makeup of tissue in disease using high-resolution infrared and x-ray imaging

  lmiller@bnl.gov

  

  Jyoti Misra

  Growth regulation by the Hippo Signaling pathway in development and cancer

  jyoti.misra@stonybrook.edu

  

  Ute Moll

  Tumor Suppressor Gene Research: Mechanism of p53 Inactivation

  ute.moll@stonybrookmedicine.edu

  

  David Montrose

  Colon cancer, inflammatory bowel disease, microbiota, metabolism

  david.montrose@stonybrookmedicine.edu

  

  Neil Nadkarni

  The NVITe lab seeks to understand relationships between various components of innate immunity and cerebrovascular dynamics in both preclinical and clinical stroke.

  neil.nadkarni@stonybrookmedicine.edu

  

  Joshua Plotkin

  Striatal microcircuitry underlying normal behavior and disorders such as OCD

  joshua.plotkin@stonybrook.edu

  

  Michelino Puopolo

  Ion channels and neuronal excitability; mechanisms of pain

  Michelino.Puopolo@StonyBrookMedicine.edu

  

  Gilbert Rahme

  Cancer epigenetics with a focus on brain tumors

  gilbert.rahme@stonybrook.edu

  

  Nancy Reich

  Signal Transduction and Activation of Gene Expression by Cytokines & Cellular Defense Responses to Viral Infection

  nancy.reich@stonybrook.edu

  

  Robert Rizzo

  Computational Research Projects in Cancer, HIV\AIDS, Influenza, and Method Development

  rizzorc@gmail.com

  

  Jessica Seeliger

  Membrane biosynthesis, structure & behavior in bacterial pathogenesis

  jessica.seeliger@stonybrook.edu

  

  Markus Seeliger

  Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging

  markus.seeliger@stonybrook.edu

  

  Eugene Serbryany

  Protein misfolding and aggregation; protein and peptide libraries and sequencing; non-native protein conformations as novel drug targets or antigens

  Eugene.Serebryany@stonybrook.edu

  

  Roger Sher

  My research is committed to studying the complexity inherent in biological systems for the purpose of improving human health, focusing on Amyotrophic Lateral Sclerosis, Alzheimer's Disease, and neurodegenerative diseases

  roger.sher@stonybrook.edu

  

  Mario Shields

  The mechanisms of development and progression of diseases affecting the exocrine pancreas, such as pancreatitis and pancreatic cancer

  mario.shields@stonybrook.edu

  

  Kenneth Shroyer

  The molecular characterization of benign, premalignant, and malignant lesions of the female genital tract

  Kenneth.Shroyer@stonybrookmedicine.edu

  

  Carlos Simmerling

  Computational Structural Biology

  carlos.simmerling@stonybrook.edu

  

  Ken-Ichi Takemaru

  Cell Signaling and Ciliogenesis in Mammalian Development, Health and Disease

  ken-ichi.takemaru@stonybrook.edu

  

  Flaminia Talos

  Specification and clonal fate analysis of prostate epithelial cells in organogenesis and cancer

  flaminia.talos@stonybrookmedicine.edu

  

  Dongyan Tan

  Structure and function of macromolecules in epigenetic regulation

  dongyan.tan@stonybrook.edu

  

  Shao-Jun Tang

  Neuron-glia interaction in pain pathogenesis induced by opioids, HIV, or antiretroviral drugs

  Shao.Tang@stonybrookmedicine.edu

  

  Gerald Thomsen

  Vertebrate Embryonic Development 

  gerald.h.thomsen@stonybrook.edu

  

  Peter Tonge

  Chemical biology, pharmacology, mechanism of drug action, anticancer and
  
  antibacterial drug discovery, positron emission tomography (PET)
  
  imaging

  peter.tonge@stonybrook.edu

  

  Styliani-Anna (Stella) Tsirka

  Neuro-immune interactions: Cross-talk between the nervous and immune systems in health and disease 

  styliani-anna.tsirka@stonybrook.edu

  

  David Tuveson

  Pancreatic cancer, experimental therapeutics, diagnostics, mouse models, cancer genetics

  dtuveson@cshl.edu

  

  Adrianus Van Der Velden

  The mammalian T cell response to Salmonella enterica serovar Typhimurium 

  a.vandervelden@stonybrook.edu

  

  Charles Vorkas

  Innate lymphocyte biology of infectious diseases and cancer; Mycobacterium tuberculosis, tick-borne diseases, and hematologic malignancies

  Charles.Vorkas@stonybrookmedicine.edu

  

  Ledong Wan

  RNA Metabolism, Pancreatic Cancer, Inflammation

  ledong.wan@stonybrook.edu

  

  Zhishan Wang

  Environmental carcinogenesis, Cancer biology and Cancer therapy

  zhishan.wang@stonybrookmedicine.edu

  

  Lonnie Wollmuth

  Molecular Mechanisms of Synaptic Function in the Brain 

  lonnie.wollmuth@stonybrook.edu

  

  Chengfeng Yang

  RNA dysfunction in carcinogenesis and resistance to cancer therapies 

  chengfeng.yang@stonybrookmedicine.edu

  

  Qiuhua Yang

  Metabolic and immune regulation of retinal degeneration

  qiuhua.yang@stonybrook.edu

  

  Vincent Yang

  Identifying the causes and treatment of gastrointestinal malignancies

  vincent.yang@stonybrookmedicine.edu

  

  Wei Yang

  Harnessing the power of multi-level proteomics to understand and prevent cancer metastasis

  wei.yang@stonybrook.edu

  

  Huichun Zhan

  Pathogenesis and treatment of myeloproliferative neoplasms

  Huichun.zhan@stonybrookmedicine.edu

• Cancer
  

  Michael Airola

  The Airola lab studies the molecular details of lipid metabolism and transport and seeks to develop new pharmacological tools that inhibit lipid-modifying enzymes for the treatment of cancer and fungal disease

  Michael.airola@stonybrook.edu

  

  Eric Brouzes

  Analyzing heterogeneity of cancer tissues

  eric.brouzes@stonybrook.edu

  

  Christopher Brownlee

  Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

  christopher.brownlee@stonybrook.edu

  

  Fei Chen

  Environmental risk factors in carcinogenesis with emphasis on metabolic and epigenetic reprograms during malignant transformation of the cells.

  Fei.Chen.1@stonybrook.edu

  

  Jun Chung

  Mechanism of cancer invasion and metastasis

  Jun.Chung@stonybrookmedicine.edu

  

  Chris Clarke

  Sphingolipid metabolism and signaling in tumorigenesis.

  Christopher.clarke@stonybrookmedicine.edu

  

  Mehdi Damaghi

  Tumor evolution and adaptation in their microenvironment using spatial single cell technologies

  Mehdi.Damaghi@stonybrook.edu

  

  Bruce Demple

  Cellular Systems to Counteract Oxidative Damage

  bruce.demple@stonybrook.edu

  

  Camila Dos Santos

  Epigenetic dependencies of normal and malignant breast development, with a focus on understanding paths to prevent cancer development and to attenuate the aggressiveness of already established cancer

  dossanto@cshl.edu

  

  Michael Frohman

  Lipid Signaling: Roles in mitochondrial biology, spermatogenesis, diabetes, immune function, the CNS, platelet activation, and cancer; - Imaging Pancreatic β-cells using metabolomics and MRI

  michael.frohman@stonybrook.edu

  

  Miguel Garcia-Diaz

  Mechanisms of mitochondrial gene expression/Mechanisms of DNA synthesis and repair

  miguel.garcia-diaz@stonybrook.edu

  

  Yusuf Hannun

  Lipid mediators of cancer cell signaling

  yusuf.hannun@stonybrookmedicine.edu

  

  Hyungjin Kim

  DNA damage repair and cancer therapeutics; mechanisms of cancer drug actions and therapy response

  Hyungjin.kim@stonybrook.edu

  

  Feng-Qian Li

  Signaling: Cell Signaling, Cancer, Stem cells, Protein trafficking and Disease

  feng-qian.li@stonybrook.edu

  

  Richard Lin

  Intracellular signaling molecules that regulate cell growth

  Richard.Lin@sunysb.edu

  

  Ke Jian (Jim) Liu

  Molecular mechanisms of metal carcinogenesis; DNA repair and somatic mutations

  kejian.liu@stonybrookmedicine.edu

  

  Ed Luk

  How cells organize chromatin structure to accommodate and control gene expression

  ed.luk@stonybrook.edu

  

  Yupo Ma

  Leukemic Stem Cells; Stem Cell Therapy

  yupo.ma@stonybrookmedicine.edu

  

  Cungui Mao

  Bioactive sphingolipids in cell growth, differentiation, apoptosis, and autophagy

  Cungui.Mao@stonybrook.edu

  

  Peng Mao

  DNA repair and cancer mutations

  Peng.Mao@stonybrookmedicine.edu

  

  Benjamin Martin

  Molecular basis of stem cell development and cancer pathogenesis

  benjamin.martin@stonybrook.edu

  Luis Martinez

  p53 alterations in cancer

  luis.martinez@stonybrookmedicine.edu

  

  W. (Todd) Miller

  Signal transduction by tyrosine kinases

  Todd.Miller@stonybrook.edu

  

  Jyoti Misra

  Growth regulation by the Hippo Signaling pathway in development and cancer

  jyoti.misra@stonybrook.edu

  

  Ute Moll

  Tumor Suppressor Gene Research: Mechanism of p53 Inactivation

  ute.moll@stonybrookmedicine.edu

  

  David Montrose

  Colon cancer, inflammatory bowel disease, microbiota, metabolism

  david.montrose@stonybrookmedicine.edu

  

  Gilbert Rahme

  Cancer epigenetics with a focus on brain tumors

  gilbert.rahme@stonybrook.edu

  

  Robert Rizzo

  Computational Research Projects in Cancer, HIV\AIDS, Influenza, and Method Development

  rizzorc@gmail.com

  

  Markus Seeliger

  Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging

  markus.seeliger@stonybrook.edu

  

  Mario Shields

  The mechanisms of development and progression of diseases affecting the exocrine pancreas, such as pancreatitis and pancreatic cancer

  mario.shields@stonybrook.edu

  

  Kenneth Shroyer

  The molecular characterization of benign, premalignant, and malignant lesions of the female genital tract

  Kenneth.Shroyer@stonybrookmedicine.edu

  

  Flaminia Talos

  Specification and clonal fate analysis of prostate epithelial cells in organogenesis and cancer

  flaminia.talos@stonybrookmedicine.edu

  

  Dongyan Tan

  Structure and function of macromolecules in epigenetic regulation

  dongyan.tan@stonybrook.edu

  

  Peter Tonge

  Chemical biology, pharmacology, mechanism of drug action, anticancer and
  
  antibacterial drug discovery, positron emission tomography (PET)
  
  imaging

  peter.tonge@stonybrook.edu

  

  David Tuveson

  Pancreatic cancer, experimental therapeutics, diagnostics, mouse models, cancer genetics

  dtuveson@cshl.edu

  

  Charles Vorkas

  Innate lymphocyte biology of infectious diseases and cancer; Mycobacterium tuberculosis, tick-borne diseases, and hematologic malignancies

  Charles.Vorkas@stonybrookmedicine.edu/td>

  

  Ledong Wan

  RNA Metabolism, Pancreatic Cancer, Inflammation

  ledong.wan@stonybrook.edu

  

  Chengfeng Yang

  RNA dysfunction in carcinogenesis and resistance to cancer therapies 

  chengfeng.yang@stonybrookmedicine.edu

  

  Vincent Yang

  Identifying the causes and treatment of gastrointestinal malignancies

  vincent.yang@stonybrookmedicine.edu

  

  Wei Yang

  Harnessing the power of multi-level proteomics to understand and prevent cancer metastasis

  wei.yang@stonybrook.edu

• Chemical Biology
  

  Elizabeth Boon

  Chemical Biology, Enzymology, Bioinorganic Chemistry, and Spectroscopy

  elizabeth.boon@stonybrook.edu

  

  Christopher Brownlee

  Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

  christopher.brownlee@stonybrook.edu

  

  Isaac Carrico

  Chemical Biology, Bioorganic Chemistry and Protein Engineering

  isaac.carrico@stonybrook.edu

  

  Bruce Demple

  Cellular Systems to Counteract Oxidative Damage

  bruce.demple@stonybrook.edu

  

  Miguel Garcia-Diaz

  Mechanisms of mitochondrial gene expression/Mechanisms of DNA synthesis and repair

  miguel.garcia-diaz@stonybrook.edu

  

  Galadriel Hovel-Miner

  Discovery of novel genes and pathways associated with drug resistance in trypanosomatid parasites

  Galadriel.Hovel-Miner@stonybrook.edu

  

  Scott Laughlin

  Chemical Biology & Neuroscience

  Scott.Laughlin@stonybrook.edu

  

  Jessica Seeliger

  Membrane biosynthesis, structure & behavior in bacterial pathogenesis

  jessica.seeliger@stonybrook.edu

  

  Markus Seeliger

  Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging

  markus.seeliger@stonybrook.edu

  

  Peter Tonge

  Chemical biology, pharmacology, mechanism of drug action, anticancer and
  
  antibacterial drug discovery, positron emission tomography (PET)
  
  imaging

  peter.tonge@stonybrook.edu

• Computational Biology
  

  Camila Dos Santos

  Epigenetic dependencies of normal and malignant breast development, with a focus on understanding paths to prevent cancer development and to attenuate the aggressiveness of already established cancer

  dossanto@cshl.edu

  

  Michael Mak

  Mechanobiology and biophysics in cancer and development; biofabrication of ultra-realistic tissues and organoids for disease modeling and regeneration; computational modeling and biophysical informatics

  michael.mak@stonybrook.edu

  

  Robert Rizzo

  Computational Research Projects in Cancer, HIV\AIDS, Influenza, and Method Development

  rizzorc@gmail.com

  

  Eugene Serbryany

  Protein misfolding and aggregation; protein and peptide libraries and sequencing; non-native protein conformations as novel drug targets or antigens

  Eugene.Serebryany@stonybrook.edu

  

  Carlos Simmerling

  Computational Structural Biology

  carlos.simmerling@stonybrook.edu

• DNA Damage and Repair
  

  Bruce Demple

  Cellular Systems to Counteract Oxidative Damage

  bruce.demple@stonybrook.edu

  

  Miguel Garcia-Diaz

  Mechanisms of mitochondrial gene expression/Mechanisms of DNA synthesis and repair

  miguel.garcia-diaz@stonybrook.edu

  

  Galadriel Hovel-Miner

  Discovery of novel genes and pathways associated with drug resistance in trypanosomatid parasites

  Galadriel.Hovel-Miner@stonybrook.edu

  

  Peng Mao

  DNA repair and cancer mutations

  Peng.Mao@stonybrookmedicine.edu

  

  Hyungjin Kim

  DNA damage repair and cancer therapeutics; mechanisms of cancer drug actions and therapy response

  Hyungjin.kim@stonybrook.edu

  

  Ke Jian (Jim) Liu

  Molecular mechanisms of metal carcinogenesis; DNA repair and somatic mutations

  kejian.liu@stonybrookmedicine.edu

  

  Thomas Rosenquist

  Genetic Analysis of Mammalian Oxidative DNA Damage Repair

  thomas.rosenquist@stonybrook.edu

  

  Carlos Simmerling

  Computational Structural Biology

  carlos.simmerling@stonybrook.edu

  

  Zhishan Wang

  Environmental carcinogenesis, Cancer biology and Cancer therapy

  zhishan.wang@stonybrookmedicine.edu

• Mitochondrial Biology
  

  Bruce Demple

  Cellular Systems to Counteract Oxidative Damage

  bruce.demple@stonybrook.edu

  

  Michael Frohman

  Lipid Signaling: Roles in mitochondrial biology, spermatogenesis, diabetes, immune function, the CNS, platelet activation, and cancer; - Imaging Pancreatic β-cells using metabolomics and MRI

  michael.frohman@stonybrook.edu

  

  Miguel Garcia-Diaz

  Mechanisms of mitochondrial gene expression/Mechanisms of DNA synthesis and repair

  miguel.garcia-diaz@stonybrook.edu

  

  Steven Glynn

  X-ray crystallography, mechanistic biochemistry and protein design techniques to uncover the operating principles of energy-dependent proteolytic machines in mitochondria

  steven.glynn@stonybrook.edu

  

  Ute Moll

  Tumor Suppressor Gene Research: Mechanism of p53 Inactivation

  ute.moll@stonybrookmedicine.edu

• Neurobiology
  

  Maricedes Acosta-Martinez

  Neuroendocrinology, Neuroinflammation, and Placenta Physiology

  Maricedes.Acosta@stonybrook.edu

  

  Mark Bowen

  Neurobiology. Protein supertertiary structure. Fluorescence microscopy.

  Mark.Bowen@StonyBrook.edu

  

  Christopher Brownlee

  Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

  christopher.brownlee@stonybrook.edu

  

  Holly Colognato

  Extracellular matrix in the brain: roles during development and during neurodegeneration

  holly.colognato@stonybrook.edu

  

  Joshua Dubnau

  The effects of healthy aging on brain function, and on the mechanisms of age related neurodegenerative disorders. We specialize in the impacts of retrotransposons and endogenous retroviruses as drivers of aging and neurodegeneration, with a particular emphasis on signaling between glia and neurons. Our model organism of choice is the fruit fly, Drosophila, mainly because flies rule.

  Joshua.Dubnau@stonybrook.edu

  

  Grigori Enikolopov

  Stem cells; neurogenesis; imaging; signal transduction

  Grigori.Enikolopov@StonyBrookMedicine.edu

  

  Shaoyu Ge

  To examine the functional integration of new neurons into brain circuits

  shaoyu.ge@stonybrook.edu

  

  Helen Hsieh

  Necrotizing Enterocolitis (NEC) and Neurodevelopment: the Role of Inflammation in Brain Development

  helen.hsieh@stonybrookmedicine.edu

  

  Martin Kaczocha

  Neuroscience, acute and chronic pain, drug development, lipid signaling

  Martin.Kaczocha@StonyBrook.edu

  

  Scott Laughlin

  Chemical Biology & Neuroscience

  Scott.Laughlin@stonybrook.edu

  

  David McKinnon

  Molecular Physiology of Neuronal Firing Properties

  David.McKinnon@stonybrook.edu

  

  Neil Nadkarni

  The NVITe lab seeks to understand relationships between various components of innate immunity and cerebrovascular dynamics in both preclinical and clinical stroke.

  neil.nadkarni@stonybrookmedicine.edu

  

  Joshua Plotkin

  Striatal microcircuitry underlying normal behavior and disorders such as OCD

  joshua.plotkin@stonybrook.edu

  

  Michelino Puopolo

  Ion channels and neuronal excitability; mechanisms of pain

  Michelino.Puopolo@StonyBrookMedicine.edu

  

  Gilbert Rahme

  Cancer epigenetics with a focus on brain tumors

  gilbert.rahme@stonybrook.edu

  

  Roger Sher

  My research is committed to studying the complexity inherent in biological systems for the purpose of improving human health, focusing on Amyotrophic Lateral Sclerosis, Alzheimer's Disease, and neurodegenerative diseases

  roger.sher@stonybrook.edu

  

  Shao-Jun Tang

  Neuron-glia interaction in pain pathogenesis induced by opioids, HIV, or antiretroviral drugs

  Shao.Tang@stonybrookmedicine.edu

  

  Styliani-Anna (Stella) Tsirka

  Neuro-immune interactions: Cross-talk between the nervous and immune systems in health and disease 

  styliani-anna.tsirka@stonybrook.edu

  

  Lonnie Wollmuth

  Molecular Mechanisms of Synaptic Function in the Brain 

  lonnie.wollmuth@stonybrook.edu

  

  Qiuhua Yang

  Metabolic and immune regulation of retinal degeneration

  qiuhua.yang@stonybrook.edu

• Signal Transduction
  

  Elizabeth Boon

  Chemical Biology, Enzymology, Bioinorganic Chemistry, and Spectroscopy

  elizabeth.boon@stonybrook.edu

  

  Mark Bowen

  Neurobiology. Protein supertertiary structure. Fluorescence microscopy.

  Mark.Bowen@StonyBrook.edu

  

  Christopher Brownlee

  Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

  christopher.brownlee@stonybrook.edu

  

  Nicholas Carpino

  Positive and Negative Regulation of T cell Receptor Signaling

  nicholas.carpino@stonybrook.edu

  

  Leonard Cheung

  Pituitary function in physiology, aging, and disease

  Leonard.Cheung@stonybrook.edu

  

  Holly Colognato

  Extracellular matrix in the brain: roles during development and during neurodegeneration

  holly.colognato@stonybrook.edu

  

  Michael Frohman

  Lipid Signaling: Roles in mitochondrial biology, spermatogenesis, diabetes, immune function, the CNS, platelet activation, and cancer; - Imaging Pancreatic β-cells using metabolomics and MRI

  michael.frohman@stonybrook.edu

  

  Chi-Kuo Hu

  We study the biology of dormancy and its interaction with development and aging, using an intriguing research organism of the African killifish.

  chi-kuo.hu@stonybrook.edu

  

  Michael Mak

  Mechanobiology and biophysics in cancer and development; biofabrication of ultra-realistic tissues and organoids for disease modeling and regeneration; computational modeling and biophysical informatics

  michael.mak@stonybrook.edu

  

  Sandeep Mallipattu

  Our research program focuses on investigating the molecular mechanisms involved in the development and progression of kidney disease.

  Sandeep.Mallipattu@stonybrookmedicine.edu

  

  W. (Todd) Miller

  Signal transduction by tyrosine kinases

  Todd.Miller@stonybrook.edu

  

  Ute Moll

  Tumor Suppressor Gene Research: Mechanism of p53 Inactivation

  ute.moll@stonybrookmedicine.edu

  

  Joshua Plotkin

  Striatal microcircuitry underlying normal behavior and disorders such as OCD

  joshua.plotkin@stonybrook.edu

  

  Mario Shields

  The mechanisms of development and progression of diseases affecting the exocrine pancreas, such as pancreatitis and pancreatic cancer

  mario.shields@stonybrook.edu

  

  Ken-Ichi Takemaru

  Cell Signaling and Ciliogenesis in Mammalian Development, Health and Disease

  ken-ichi.takemaru@stonybrook.edu

  

  Qiuhua Yang

  Metabolic and immune regulation of retinal degeneration

  qiuhua.yang@stonybrook.edu

• Structural Biology
  

  Ivet Bahar

  Our lab is interested in computer-aided design and development of small molecule modulators of protein function including orthosteric and allosteric drugs, and in modeling biomolecular interactions and their systemic effects at multiple scales.

  ivet.bahar@stonybrook.edu

  

  Elizabeth Boon

  Chemical Biology, Enzymology, Bioinorganic Chemistry, and Spectroscopy

  elizabeth.boon@stonybrook.edu

  

  Mark Bowen

  Neurobiology. Protein supertertiary structure. Fluorescence microscopy.

  Mark.Bowen@StonyBrook.edu

  

  Christopher Brownlee

  Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

  christopher.brownlee@stonybrook.edu

  

  Miguel Garcia-Diaz

  Mechanisms of mitochondrial gene expression/Mechanisms of DNA synthesis and repair

  miguel.garcia-diaz@stonybrook.edu

  

  Steven Glynn

  X-ray crystallography, mechanistic biochemistry and protein design techniques to uncover the operating principles of energy-dependent proteolytic machines in mitochondria

  steven.glynn@stonybrook.edu

  

  Leemor Joshua-Tor

  Structural Biology of gene expression, DNA replication, and small RNA biology

  leemor@cshl.edu

  

  Wali Karzai

  Biochemistry and Structural biology of RNA-Protein Interactions, Translational Control of Gene Expression, and Drug Discovery

  Wali.Karzai@stonybrook.edu

  

  W. (Todd) Miller

  Signal transduction by tyrosine kinases

  Todd.Miller@stonybrook.edu

  

  Lisa Miller

  The chemical makeup of tissue in disease using high-resolution infrared and x-ray imaging

  lmiller@bnl.gov

  

  Robert Rizzo

  Computational Research Projects in Cancer, HIV\AIDS, Influenza, and Method Development

  rizzorc@gmail.com

  

  Markus Seeliger

  Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging

  markus.seeliger@stonybrook.edu

  

  Eugene Serbryany

  Protein misfolding and aggregation; protein and peptide libraries and sequencing; non-native protein conformations as novel drug targets or antigens

  Eugene.Serebryany@stonybrook.edu

  

  Carlos Simmerling

  Computational Structural Biology

  carlos.simmerling@stonybrook.edu

  

  Dongyan Tan

  Structure and function of macromolecules in epigenetic regulation

  dongyan.tan@stonybrook.edu